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Travel health

Atovaquone / proguanil (Malarone) PGD.

Deliver a professional malaria prevention service through Scripter's structured consultation pathway. Supply: Atovaquone with proguanil tablets, daily.

Illustration: Malaria prevention

What is Atovaquone / proguanil (Malarone)?

Atovaquone/proguanil is the best-tolerated daily antimalarial and has the shortest course, starting one to two days before travel and stopping a week after return. That makes it the usual first choice for short trips, with a paediatric strength available for children.

The condition it treats

Malaria is a mosquito-borne parasitic disease that kills travellers every year, with falciparum malaria able to turn fatal within days of first fever. Prevention stacks bite avoidance with chemoprophylaxis matched to the destination's resistance patterns.

How the service runs on Scripter

Patients book online, complete the pre-consultation questionnaire, and the guided pathway walks the practitioner through the malaria prevention consultation with the screening and counselling steps built in. The supply decision, the record and any GP notification are produced in the same flow, documented against the exact protocol version in force.

Training and eligibility requirements.

Who can deliver this service, and who it can be delivered to. The governing PGD document defines the definitive inclusion, exclusion and supply criteria; the Scripter consultation pathway enforces them, and every consultation is documented against the protocol version it ran under.

Practitioner training
✓Registered healthcare professional from a profession authorised to supply under PGDs (Schedule 16, Part 4 of the Human Medicines Regulations 2012), such as a pharmacist, nurse, paramedic or physiotherapist, with current registration with their professional regulator
✓Practising from premises suitable for the service, such as registered pharmacy premises or a registered clinic
✓Assessed clinical competency for this service, declared and reviewed as part of PGD authorisation
✓Sign-off against the current version of this PGD in Scripter before first supply; sign-offs expire automatically when the protocol is updated, and the platform notifies everyone affected
✓In-date basic life support and safeguarding training
✓Indemnity arrangements covering the service
Patient eligibility
✓Travellers to destinations where atovaquone/proguanil is a recommended option under current national guidance
✓Renal impairment, pregnancy and weight-based paediatric dosing assessed per the governing PGD
✓Started one to two days before entry and continued for seven days after leaving
✓Taken with food or milk each day; bite prevention and fever-warning counselling completed

Atovaquone / proguanil (Malarone) PGD questions

Why is the course so short?+

Atovaquone/proguanil acts on the liver stage of the parasite, so only a week of post-travel cover is needed instead of four.

Is it suitable for children?+

Yes, with a paediatric tablet dosed by weight, within the limits set by the governing PGD.

Why take it with food?+

Absorption depends on fat in the meal; a dose on an empty stomach may not give full protection.

More travel health PGDs.

Related protocols in the same category, all delivered through the same platform.

Run a malaria prevention service without the paperwork.

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