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Upper respiratory infections

Clarithromycin PGD.

Deliver a professional sore throat / tonsillitis in penicillin allergy service through Scripter's structured consultation pathway. Supply: Clarithromycin tablets or oral suspension.

Illustration: Sore throat / tonsillitis in penicillin allergy

What is Clarithromycin?

Clarithromycin is a macrolide antibiotic and the standard alternative for streptococcal sore throat when the patient is allergic to penicillin, covering the same organisms by a different mechanism.

The condition it treats

Streptococcal tonsillitis in a penicillin-allergic patient still deserves treatment when scoring criteria are met; the allergy changes the drug, not the decision framework.

How the service runs on Scripter

Patients book online, complete the pre-consultation questionnaire, and the guided pathway walks the practitioner through the sore throat / tonsillitis in penicillin allergy consultation with the screening and counselling steps built in. The supply decision, the record and any GP notification are produced in the same flow, documented against the exact protocol version in force.

Training and eligibility requirements.

Who can deliver this service, and who it can be delivered to. The governing PGD document defines the definitive inclusion, exclusion and supply criteria; the Scripter consultation pathway enforces them, and every consultation is documented against the protocol version it ran under.

Practitioner training
✓Registered healthcare professional from a profession authorised to supply under PGDs (Schedule 16, Part 4 of the Human Medicines Regulations 2012), such as a pharmacist, nurse, paramedic or physiotherapist, with current registration with their professional regulator
✓Practising from premises suitable for the service, such as registered pharmacy premises or a registered clinic
✓Assessed clinical competency for this service, declared and reviewed as part of PGD authorisation
✓Sign-off against the current version of this PGD in Scripter before first supply; sign-offs expire automatically when the protocol is updated, and the platform notifies everyone affected
✓In-date basic life support and safeguarding training
✓Indemnity arrangements covering the service
Patient eligibility
✓Patients meeting the same FeverPAIN/Centor thresholds as the penicillin pathway
✓Documented or reported penicillin allergy
✓Interacting medicines screened; clarithromycin interacts with statins, some anticoagulants and QT-prolonging drugs
✓Safety-netting and GP notification completed

Clarithromycin PGD questions

Why does the consultation ask about statins?+

Clarithromycin blocks the enzyme that clears several statins, raising muscle-damage risk; the interaction screen is a required step, and some combinations mean a different plan.

Is the allergy verified?+

The pathway records the nature of the reported reaction; a genuine allergy routes here, while a mislabelled intolerance is flagged for the record without blocking safe care.

Same criteria as penicillin V?+

Exactly the same scoring and red flags; only the agent differs.

More upper respiratory infections PGDs.

Related protocols in the same category, all delivered through the same platform.

Run a sore throat / tonsillitis in penicillin allergy service without the paperwork.

See the consultation pathway, the sign-off tracking and the record it produces in a free 30-minute demo.

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